TY - CHAP M1 - Book, Section TI - Modified-Release Drug Products and Drug Devices A1 - Ding, Hong A2 - Shargel, Leon A2 - Yu, Andrew B.C. PY - 2016 T2 - Applied Biopharmaceutics & Pharmacokinetics, 7e AB - Define modified-release drug products.Differentiate between conventional, immediate-release, extended-release, delayed-release, and targeted drug products.Explain the advantages and disadvantages of extended-release drug products.Describe the kinetics of extended-release drug products compared to immediate-release drug products.Explain when an extended-release drug product should contain an immediate-release drug dose.Explain why extended-release beads in capsule formulation may have a different bioavailability profile compared to an extended-release tablet formulation of the same drug.Describe several approaches for the formulation of an oral extended-release drug product.Explain why a transdermal drug product (patch) may be considered an extended-release drug product.Describe the components of a transdermal drug delivery system.Explain why an extended-release formulation of a drug may have a different efficacy profile compared to the same dose of drug given in as a conventional, immediate-release, oral dosage form in multiple doses.List the studies that might be required for the development of an extended-release drug product.List the several achievements on the drug devices based on the modified-release drug design. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/03/28 UR - accesspharmacy.mhmedical.com/content.aspx?aid=1117901135 ER -