TY - CHAP M1 - Book, Section TI - Nitrogen: Nucleotide Metabolism A1 - King, Michael W. PY - 2014 T2 - Integrative Medical Biochemistry Examination and Board Review AB - High-Yield Terms5-phosphoribosyl-1-pyrophosphate (PRPP): activated form of ribose used in de novo synthesis of purine and pyrimidine nucleotidesGout: a disorder that is related to excess production and deposition of uric acid crystals; does not occur in the absence of hyperuricemiaSevere-combined immunodeficiency (SCID): a disorder related to defects in the activity of the purine nucleotide catabolism enzyme, adenosine deaminase (ADA)Tumor lysis syndrome (TLS): potentially fatal condition characterized by acute urate nephropathy, resulting from significant increases in purine nucleotide degradation from dying cancer cells SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/03/29 UR - accesspharmacy.mhmedical.com/content.aspx?aid=1122104490 ER -