TY - CHAP M1 - Book, Section TI - Venous Thromboembolism A1 - Witt, Daniel M. A1 - Clark, Nathan P. A1 - Vazquez, Sara R. A2 - DiPiro, Joseph T. A2 - Talbert, Robert L. A2 - Yee, Gary C. A2 - Matzke, Gary R. A2 - Wells, Barbara G. A2 - Posey, L. Michael PY - 2017 T2 - Pharmacotherapy: A Pathophysiologic Approach, 10e AB - Patient Care Process for the Treatment of Venous ThromboembolismCollectPatient characteristics (e.g., age, sex, pregnant)Patient history (past medical, family, social — dietary habits including intake of vitamin K containing foods (see Table 19-13), tobacco/ethanol use)Current medications including aspirin/OTC NSAID use and prior anticoagulant medication useObjective dataBP, heart rate (HR), respiratory rate (RR), O2-sat, height, weightLabs (e.g. Hgb, Scr, platelets, aPTT, PT)Do NOT order hypercoagulability testsObjective confirmation of VTE (see Fig 19-6 and 19-7)AssessHemodynamic stability (e.g. SBP 110 bpm, O2-sat <90%, RR), evidence of limb ischemiaPresence of active bleeding and/or bleeding risk factors (see Figure 19-8, Table 19-10)Presence of VTE provoking factors (e.g. recent surgery, plaster casting of lower extremity, indwelling catheter, cancer, pregnancy, estrogen use, prolonged immobility, recent hospitalization)Ability/willingness to self-inject LMWH/fondaparinuxAbility/willingness to pay for various anticoagulation therapy optionsAbility/willingness to obtain appropriate laboratory monitoring (e.g. INR for warfarin)Emotional status (e.g. presence of anxiety, depression)PlanDrug therapy regimen including specific anticoagulant(s), dose, route, frequency, and duration; (see Figs 19-8, 19-9, Tables 19-3, 19-4, 19-6, 19-8, 19-9)Monitoring parameters including efficacy (e.g. INR results, pain control, limb swelling, shortness of breath), safety (bleeding, VTE recurrence), and timing of assessmentsPatient education (e.g. purpose of treatment, dietary and lifestyle modification, invasive procedures, drug therapy; see Table 19-5)Self-monitoring for resolution of VTE symptoms, occurrence of bleeding, when to seek emergency medical attentionReferals to other providers when appropriate (e.g. thrombosis specialist, behavioral health, dietician)ImplementProvide patient education regarding all elements of treatment planUse motivational interviewing and coaching strategies to maximize adherenceSchedule follow-up (e.g. INR tests [warfarin], Scr [DOACs], adherence assessment, bleeding risk assessment, duration of therapy assessment)Follow-up: Monitor and EvaluateResolution of VTE symptoms (e.g. shortness of breath, chest pain, swelling, redness, pain)Presence of adverse effects (e.g. bleeding, GI upset [dabigatran])INR results (adjust warfarin dose as needed to keep between 2-3)Patient adherence to treatment plan using multiple sources of informationDuration of therapy after 90 days SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/04/16 UR - accesspharmacy.mhmedical.com/content.aspx?aid=1157514777 ER -