TY - CHAP M1 - Book, Section TI - Systemic Lupus Erythematosus A1 - Resman-Targoff, Beth H. A2 - DiPiro, Joseph T. A2 - Talbert, Robert L. A2 - Yee, Gary C. A2 - Matzke, Gary R. A2 - Wells, Barbara G. A2 - Posey, L. Michael PY - 2017 T2 - Pharmacotherapy: A Pathophysiologic Approach, 10e AB - Patient Care Process for the Management of Systemic Lupus ErythematosusCollectPatient characteristics (e.g., age, race, sex, pregnancy status)Patient history (past medical, pregnancies and outcomes, symptoms, family, social—dietary habits, alcohol and tobacco use)Current medications and prior lupus medication useImmunization historyObjective data (see Clinical Presentation and Table 87-1)Blood pressure (BP), heart rate, height, weight, and BMI; other physical exam findingsLabs (metabolic panel, Scr, BUN, urinalysis, CBC, ANA, antiphospholipid antibodies, direct Coomb's test, other lupus-associated antibodies, complement, inflammatory markers (ESR, CRP)Other diagnostic tests when indicated (e.g., ECG, CXR, skin or kidney biopsy)AssessPresence of cutaneous, renal, neurologic, hematologic, cardiac, or pleural manifestations of lupusEvidence of antiphospholipid syndrome (thromboembolic events, miscarriages)Current medications that could be associated with drug-induced lupusAppropriateness and effectiveness of current lupus regimen (see Figures 87-2 and 87-3)Psychological effects of lupusPlan*Goals of treatmentTailored lifestyle modifications (e.g., diet, exercise, weight management, protection from sun, smoking cessation, keeping warm if Raynaud phenomenon occurs)Drug therapy regimen including specific medications based on disease manifestations, dose, route, frequency, and duration; specify the continuation and discontinuation of existing therapies (see Figures 87-2 and 87-3 and Tables 87-2 and 87-3)Monitoring parameters including efficacy (e.g., skin manifestations, cardiovascular events, thromboembolic events, miscarriages, kidney health, neurologic events), safety (medication-specific adverse effects), and timeframePatient education (e.g., purpose of treatment, dietary and lifestyle modifications, drug therapy, pregnancy considerations, osteoporosis prevention if taking corticosteroids)Self-monitoring of skin and BP—where and how to record resultsImmunizations as needed; consider timing of live vaccines with respect to immunosuppressive drug useReferrals to other providers when appropriate (e.g., physician, dietician)Implement*Provide patient education regarding all elements of treatment planUse motivational interviewing and coaching strategies to maximize adherenceSchedule follow-up based on severity of symptoms and stabilityFollow-up: Monitor and EvaluateDetermine goal attainment based on disease manifestationsPresence of adverse effectsOccurrence of CV events and development/progression of kidney or other organ impairmentPatient adherence to treatment plan using multiple sources of information*Collaborate with patient, caregivers, and other health professionals SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/04/18 UR - accesspharmacy.mhmedical.com/content.aspx?aid=1148578332 ER -