TY  - CHAP
M1  - Book, Section
TI  - Carcinoma of Unknown Primary
A1  - Varadhachary, Gauri R.
A1  - Abbruzzese, James L.
A2  - Jameson, J. Larry
A2  - Fauci, Anthony S.
A2  - Kasper, Dennis L.
A2  - Hauser, Stephen L.
A2  - Longo, Dan L.
A2  - Loscalzo, Joseph
PY  - 2018
T2  - Harrison's Principles of Internal Medicine, 20e
AB  - Carcinoma  of  unknown  primary  (CUP)  is  a  biopsy-proven  malignancy  for  which  the  anatomic  site  of  origin  remains  unidentified  after  a  focused  search.  CUP  is  one  of  the  10  most  frequently  diagnosed  cancers  worldwide,  accounting  for  3–5%  of  all  cancers.  Most  investigators  limit  CUP  to  epithelial  and  undifferentiated  cancers  and  do  not  include  lymphomas,  metastatic  melanomas,  and  metastatic  sarcomas  because  these  cancers  have  specific  histology-  and  stage-based  treatments  that  guide  management  even  in  the  absence  of  a  primary  cancer.  
SN  - 
PB  - McGraw-Hill Education
CY  - New York, NY
Y2  - 2024/04/19
UR  - accesspharmacy.mhmedical.com/content.aspx?aid=1160012087
ER  -