TY  - CHAP
M1  - Book, Section
TI  - Diseases Caused by Gram-Negative Enteric Bacilli
A1  - Russo, Thomas A.
A1  - Johnson, James R.
A2  - Jameson, J. Larry
A2  - Fauci, Anthony S.
A2  - Kasper, Dennis L.
A2  - Hauser, Stephen L.
A2  - Longo, Dan L.
A2  - Loscalzo, Joseph
PY  - 2018
T2  - Harrison's Principles of Internal Medicine, 20e
AB  - The  post-antibiotic  era  has  begun.  For  most  people,  this  is  the  first  time  in  their  lives  that  an  effective  treatment  for  a  bacterial  infection  may  not  exist.  The  Enterobacteriaceae  are  at  the  forefront  of  this  evolving  public  health  crisis.  For  example,  the  Centers  for  Disease  Control  and  Prevention  (CDC)  and  the  World  Health  Organization  (WHO)  have  designated  carbapenem-resistant  Enterobacteriaceae  as  representing  a  threat  level  of  “urgent”  and  “priority  one,  critical,”  respectively.  Enterobacteriaceae  are  responsible  for  a  significant  proportion  of  the  deaths  attributed  to  resistant  bacteria,  the  number  of  which  has  been  estimated  at  23,000  and  25,000  annually  in  the  United  States  and  the  European  Union,  respectively,  with  numbers  three-  to  fivefold  greater  (per  capita)  in  low-  and  middle-income  countries  (e.g.,  Thailand).  These  pathogens  cause  a  wide  variety  of  infections  involving  diverse  anatomic  sites  in  both  healthy  and  compromised  hosts.  Therefore,  a  thorough  knowledge  of  clinical  presentations  and  appropriate  therapeutic  choices  is  necessary  for  optimal  outcomes.  Escherichia  coli,  Klebsiella,  Proteus,  Enterobacter,  Serratia,  Citrobacter,  Morganella,  Providencia,  Cronobacter,  and  Edwardsiella  are  enteric  gram-negative  bacilli  (GNB)  that  are  members  of  the  family  Enterobacteriaceae.  Salmonella,  Shigella,  and  Yersinia,  also  in  the  family  Enterobacteriaceae,  are  discussed  in  Chaps.  160,  161,  and  166,  respectively.  
SN  - 
PB  - McGraw-Hill Education
CY  - New York, NY
Y2  - 2024/04/19
UR  - accesspharmacy.mhmedical.com/content.aspx?aid=1160013505
ER  -