TY - CHAP M1 - Book, Section TI - Histamine, Serotonin, Drugs Used in Obesity, & the Ergot Alkaloids A1 - Katzung, Bertram G. A1 - Kruidering-Hall, Marieke A1 - Trevor, Anthony J. PY - 2019 T2 - Katzung & Trevor's Pharmacology: Examination & Board Review, 12e AB - Autacoids are endogenous molecules that do not fall into traditional autonomic groups. They do not act on cholinoceptors or adrenoceptors but have powerful pharmacologic effects on smooth muscle and other tissues. Histamine and serotonin (5-hydroxytryptamine; 5-HT) are the most important amine autacoids. The drugs used in obesity do not have significant smooth muscle effects but have some properties in common with the histamine and serotonin groups. The ergot alkaloids are a heterogeneous group of drugs (not autacoids) that interact with serotonin receptors, dopamine receptors, and α receptors. They are included in this chapter because of their effects on serotonin receptors and on smooth muscle. Peptide and eicosanoid autacoids are discussed in Chapters 17 and 18. Nitric oxide is discussed in Chapter 19. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/03/28 UR - accesspharmacy.mhmedical.com/content.aspx?aid=1156528328 ER -