TY - CHAP M1 - Book, Section TI - Antimycobacterial Drugs A1 - Katzung, Bertram G. A1 - Kruidering-Hall, Marieke A1 - Trevor, Anthony J. PY - 2019 T2 - Katzung & Trevor's Pharmacology: Examination & Board Review, 12e AB - The chemotherapy of infections caused by Mycobacterium tuberculosis, M leprae, and M avium-intracellulare is complicated by numerous factors, including (1) limited information about the mechanisms of antimycobacterial drug actions; (2) the development of resistance; (3) the slow growth & intracellular location of mycobacteria; (4) the chronic nature of mycobacterial disease, which requires protracted drug treatment and is associated with drug toxicities; and (5) patient compliance. Chemotherapy of mycobacterial infections almost always involves the use of drug combinations to delay the emergence of resistance and to enhance antimycobacterial efficacy. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/03/28 UR - accesspharmacy.mhmedical.com/content.aspx?aid=1156530426 ER -