TY - CHAP M1 - Book, Section TI - Antibacterials, Antifungals, and Antivirals A1 - Stork, Christine M. A2 - Nelson, Lewis S. A2 - Howland, Mary Ann A2 - Lewin, Neal A. A2 - Smith, Silas W. A2 - Goldfrank, Lewis R. A2 - Hoffman, Robert S. PY - 2019 T2 - Goldfrank's Toxicologic Emergencies, 11e AB - The introduction of penicillin in the 1940s revolutionized the care of patients with infectious diseases. Antimicrobials, including all categories of antibacterials, antifungals, and antivirals, significantly improve the clinical care and ­outcome of infected patients. Since early in their introduction, the development of antimicrobial-resistant strains of these pathogens has driven an increase in the number of antimicrobials necessary. This, in turn, continues to increase the overall potential for toxicity after use. Fortunately, with most antimicrobials, toxicity due to acute overdose is limited and chronic therapeutic doses are safe. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/03/28 UR - accesspharmacy.mhmedical.com/content.aspx?aid=1163012572 ER -