TY - CHAP M1 - Book, Section TI - Antimicrobial Chemotherapy A1 - Riedel, Stefan A1 - Hobden, Jeffery A. A1 - Miller, Steve A1 - Morse, Stephen A. A1 - Mietzner, Timothy A. A1 - Detrick, Barbara A1 - Mitchell, Thomas G. A1 - Sakanari, Judy A. A1 - Hotez, Peter A1 - Mejia, Rojelio PY - 2019 T2 - Jawetz, Melnick, & Adelberg's Medical Microbiology, 28e AB - Drugs have been used for the treatment of infectious diseases since the 17th century (eg, quinine for malaria and emetine for amebiasis); however, chemotherapy as a science began in the first decade of the 20th century with understanding of the principles of selective toxicity, the specific chemical relationships between microbial pathogens and drugs, the development of drug resistance, and the role of combined therapy. Experiments by the German physician and scientist Paul Erlich led to the arsphenamines for syphilis, the first planned chemotherapeutic regimen. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/04/18 UR - accesspharmacy.mhmedical.com/content.aspx?aid=1163281629 ER -