TY  - CHAP
M1  - Book, Section
TI  - Tuberculosis
A1  - Cook, Kristen
A2  - Sutton, S. Scott
PY  - 2020
T2  - McGraw Hill’s NAPLEX® Review Guide, 4e
AB  - Tuberculosis  (TB)  is  an  infection  caused  by  the  acid-fast  bacillus  (AFB)  Mycobacterium  tuberculosis.  Transmission  of  TB  is  person  to  person  through  inhalation  of  droplet  nuclei  in  the  air.  The  majority  of  patients  infected  with  M.  tuberculosis  develops  latent  TB  infection  and  do  not  develop  active,  symptomatic,  disease.  Approximately  10%  of  patients  develop  active  disease  if  not  treated  with  isoniazid.  Risk  of  active  disease  is  highest  in  the  first  2  years  after  infection.  HIV  infection  is  a  significant  risk  factor  for  progression  to  active  disease.  T  lymphocytes,  especially  CD4+  cells,  are  important  in  mounting  an  immune  response  to  TB.  Tumor  necrosis  factor  alpha  and  interferon  gamma  are  cytokines  that  are  involved  in  the  body’s  immune  response  to  TB  as  well.  
SN  - 
PB  - McGraw-Hill Education
CY  - New York, NY
Y2  - 2024/04/16
UR  - accesspharmacy.mhmedical.com/content.aspx?aid=1179734401
ER  -