TY - CHAP M1 - Book, Section TI - Pancreatic Hormones, Antidiabetic Drugs, & Glucagon A1 - Katzung, Bertram G. A1 - Kruidering-Hall, Marieke A1 - Tuan, Rupa Lalchandani A1 - Vanderah, Todd W. A1 - Trevor, Anthony J. PY - 2021 T2 - Katzung & Trevor's Pharmacology: Examination & Board Review, 13e AB - In the endocrine pancreas, the islets of Langerhans produce several types of hormones. The hormones include insulin, the anabolic hormone (produced by B or beta cells); glucagon, the hyperglycemic factor (A or alpha cells); amylin, which modulates appetite (beta cells); somatostatin, the universal inhibitor of secretion (delta cells); and pancreatic polypeptide, facilitating digestion (F cells). Of these, the B (insulin-producing) cells are the most numerous.The most common pancreatic disease requiring pharmacologic therapy is diabetes mellitus, a deficiency of insulin production or effect. Diabetes is treated with several parenteral formulations of insulin and oral or parenteral noninsulin antidiabetic agents. Glucagon, a hormone that affects the liver, cardiovascular system, and gastrointestinal tract, can be used to treat severe hypoglycemia. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/03/29 UR - accesspharmacy.mhmedical.com/content.aspx?aid=1180557661 ER -