TY - CHAP M1 - Book, Section TI - Chapter 10. Variability & Bias A1 - Greenberg, Raymond S. A1 - Daniels, Stephen R. A1 - Flanders, W. Dana A1 - Eley, John William A1 - Boring, John R. PY - 2005 T2 - Medical Epidemiology, 4e AB - Validity is the extent to which a measurement or study reaches the correct conclusion. Bias is a systematic error that occurs in a study and leads to a distorted result. Selection bias is a distortion in the results of a study that arises because of the manner in which the subjects are sampled. Information (or misclassification) bias is a distortion in the results of a study that arises because of the manner in which data are collected or classified. When errors in classification of exposure or disease status do not depend on the other variable, any bias is referred to as nondifferential, and tends to underestimate the association. When errors in classification of exposure or disease status depend upon the other variable, any bias is referred to as differential, and may lead to over- or underestimating the association. Confounding is the mixing of the influence of an extraneous factor with the effect of the exposure of interest. SN - PB - The McGraw-Hill Companies CY - New York, NY Y2 - 2024/04/23 UR - accesspharmacy.mhmedical.com/content.aspx?aid=546168 ER -