TY  - CHAP
M1  - Book, Section
TI  - Antidotes in Depth (A42): Potassium Iodide
A1  - Rella, Joseph G.
A2  - Nelson, Lewis S.
A2  - Lewin, Neal A.
A2  - Howland, Mary Ann
A2  - Hoffman, Robert S.
A2  - Goldfrank, Lewis R.
A2  - Flomenbaum, Neal E.
PY  - 2011
T2  - Goldfrank's Toxicologic Emergencies, 9e
AB  - When  a  nuclear  reactor  experiences  a  catastrophic  failure,  an  uncontrolled  release  of  nuclear  fission  products  such  as  radioactive  iodine  (eg,  131I)  may  occur  (Fig.  A42–1).  Monitoring  of  the  exposed  population  of  Belarus,  Russia,  following  the  Chernobyl  meltdown  of  the  reactor  in  1986  revealed  almost  a  100-fold  increase  in  the  incidence  of  thyroid  cancer  among  children,  echoing  similar  long-term  effects  of  the  nuclear  destruction  of  Hiroshima  and  Nagasaki  in  1945.4  Iodine  is  a  solid,  bimolecular  halogen  that  sublimates  under  standard  conditions.  Potassium  iodide  (KI),  the  most  commonly  available  iodide  salt,  has  been  "generally  recognized  as  safe"  by  the  Food  and  Drug  Administration  (FDA)  for  nearly  40  years.  Potassium  iodide  is  recommended  to  prevent  the  uptake  of  radioactive  iodine  into  the  thyroid  in  order  to  reduce  the  future  risk  of  thyroid  cancer.  
SN  - 
PB  - The McGraw-Hill Companies
CY  - New York, NY
Y2  - 2021/02/28
UR  - accesspharmacy.mhmedical.com/content.aspx?aid=6539505
ER  -