TY - CHAP M1 - Book, Section TI - Chapter 35. Estimating Renal Function A1 - McNatty, Danny A2 - Sutton, S. Scott PY - 2011 T2 - McGraw-Hill's NAPLEX® Review Guide AB - Estimating renal function is of great importance for patients taking renally eliminated medications. The glomerular filtration rate (GFR) is an effective indicator of renal function and normal values are approximately 130 mL/min/1.73 m2 for men and 120 mL/min/1.73 m2 for women.1 GFR cannot be directly measured; therefore other measurements must be used to approximate renal function. The gold standard for approximating GFR is the inulin clearance method.2 Inulin is filtered by the glomerulus and is not secreted or reabsorbed, making it an ideal agent for approximating GFR. GFR approximation via inulin clearance is rarely done because it is costly, invasive, and requires a great deal of technical expertise.3 Other markers used to estimate GFR include iothalamate, iohexol, and ethylenediaminetetraacetic acid. Like inulin, these agents are expensive and have limited availability, making them impractical in the clinical setting. SN - PB - The McGraw-Hill Companies CY - New York, NY Y2 - 2024/03/28 UR - accesspharmacy.mhmedical.com/content.aspx?aid=7253103 ER -