TY - CHAP M1 - Book, Section TI - Chapter 29. Antipsychotic Agents & Lithium A1 - Trevor, Anthony J. A1 - Katzung, Bertram G. A1 - Kruidering-Hall, Marieke M. A1 - Masters, Susan B. PY - 2013 T2 - Katzung & Trevor's Pharmacology: Examination & Board Review, 10e AB - The antipsychotic drugs (neuroleptics) are used in schizophrenia and are also effective in the treatment of other psychoses and agitated states. Older drugs have high affinity for dopamine D2 receptors, whereas newer antipsychotic drugs have greater affinity for serotonin5-HT2 receptors. Although schizophrenia is not cured by drug therapy, the symptoms, including thought disorder, emotional withdrawal, and hallucinations or delusions, may be ameliorated by antipsychotic drugs. Unfortunately, protracted therapy (years) is often needed and can result in severe toxicity in some patients. In bipolar affective disorder, although lithium has been the mainstay of treatment for many years, the use of newer antipsychotic agents and of several antiseizure drugs is increasing. SN - PB - The McGraw-Hill Companies CY - New York, NY Y2 - 2024/03/29 UR - accesspharmacy.mhmedical.com/content.aspx?aid=56982301 ER -