TY  - CHAP
M1  - Book, Section
TI  - Chapter 42. Drugs that Affect Bone Mineral Homeostasis
A1  - Trevor, Anthony J.
A1  - Katzung, Bertram G.
A1  - Kruidering-Hall, Marieke M.
A1  - Masters, Susan B.
PY  - 2013
T2  - Katzung & Trevor's Pharmacology: Examination & Board Review, 10e
AB  - Calcium  and  phosphorus,  the  2  major  elements  of  bone,  are  crucial  not  only  for  the  mechanical  strength  of  the  skeleton  but  also  for  the  normal  function  of  many  other  cells  in  the  body.  Accordingly,  a  complex  regulatory  mechanism  has  evolved  to  tightly  regulate  calcium  and  phosphate  homeostasis.  Parathyroid  hormone  (PTH)  and  vitamin  D  are  primary  regulators  (Figure  42–1),  whereas  calcitonin,  glucocorticoids,  and  estrogens  play  secondary  roles.  These  hormones  or  drugs  that  mimic  or  suppress  their  actions  are  used  in  the  treatment  of  bone  mineral  disorders  (eg,  osteoporosis,  rickets,  osteomalacia,  Paget's  disease),  as  are  several  nonhormonal  agents.  
SN  - 
PB  - The McGraw-Hill Companies
CY  - New York, NY
Y2  - 2024/04/20
UR  - accesspharmacy.mhmedical.com/content.aspx?aid=56983555
ER  -