TY - CHAP M1 - Book, Section TI - Chapter 5. Advanced Cardiac Life Support A1 - Hughes, Darrel W. A1 - Attridge, Rebecca L. A2 - Attridge, Rebecca L. A2 - Miller, Monica L. A2 - Moote, Rebecca A2 - Ryan, Laurajo PY - 2013 T2 - Internal Medicine: A Guide to Clinical Therapeutics AB - 4 rhythms produce pulseless cardiac arrest: ventricular fibrillation (VF), pulseless ventricular tachycardia (VT), pulseless electrical activity (PEA), & asystoleKey elements to survival (chain of survival) in patient with cardiac arrest (JAMA 1984;251:1723) Early access; early cardiopulmonary resuscitation (CPR): compressions, airway, breathing (CAB) (Circulation 2010; 122:S250); early defibrillation (10% ↓ in successful intervention for every 1min delay); early advanced cardiac life support (ACLS)Other elements associated with survival Location of cardiac arrest: in-hospital > community (3–4-fold delay in initiation of pharmacotherapy for community cardiac arrest); witnessed > unwitnessedInitial cardiac rhythmPreexisting medical conditionsAdult cardiopulmonary arrest usually results from an arrhythmia secondary to thrombosis or pulmonary embolismGoals of ACLS: sustained return of spontaneous circulation (ROSC), limiting end-organ damage, survival to hospital dischargeRole of drug therapy: enhance chance of ROSC, facilitate defibrillationPrompt delivery of CPR followed by defibrillation ↑ survival in patients with pulseless VT/VF SN - PB - The McGraw-Hill Companies CY - New York, NY Y2 - 2024/04/20 UR - accesspharmacy.mhmedical.com/content.aspx?aid=57285942 ER -