TY  - CHAP
M1  - Book, Section
TI  - Chapter 34. Tuberculosis
A1  - Erdman, Sharon M.
A2  - Attridge, Rebecca L.
A2  - Miller, Monica L.
A2  - Moote, Rebecca
A2  - Ryan, Laurajo
PY  - 2013
T2  - Internal Medicine: A Guide to Clinical Therapeutics
AB  - Most  cases  of  human  tuberculosis  (TB)  caused  by  Mycobacterium  tuberculosis  (MTB);  Mycobacterium  spp.  are  thin,  rod-shaped  bacteria  with  hydrophobic  cells  walls  →  resistant  to  decolorization  during  Gram  staining  (acid-fast  bacilli  [AFB])Risks  for  developing  TB  infection  after  exposure  include  proximity  to  &  infectiousness  of  TB  patient,  duration  of  exposure,  immunocompetence  of  exposed  individual;  risk  of  developing  active  TB  infection  highest  w/in  2y  of  exposure;  10%  of  patients  who  acquire  TB  develop  active  infection  without  chemoprophylaxisCutaneous  TB  occurs  via  direct  inoculation  through  skinTB  exists  as  rapidly  growing  extracellular  organisms  (in  cavities,  where  resistance  may  exist),  slow-growing  organisms  (in  acidic/necrotic  tissue,  often  cause  for  treatment  failure/relapse),  or  dormant  organisms  (alternating  periods  of  dormancy  &  growth  →  treatment  failure/relapse  with  inadequate  therapy)  
SN  - 
PB  - The McGraw-Hill Companies
CY  - New York, NY
Y2  - 2024/04/19
UR  - accesspharmacy.mhmedical.com/content.aspx?aid=57292636
ER  -