TY - CHAP M1 - Book, Section TI - Principles and Techniques Applied to Enhance Elimination A1 - Goldfarb, David S. A1 - Ghannoum, Marc A2 - Hoffman, Robert S. A2 - Howland, Mary Ann A2 - Lewin, Neal A. A2 - Nelson, Lewis S. A2 - Goldfrank, Lewis R. PY - 2015 T2 - Goldfrank's Toxicologic Emergencies, 10e AB - Enhancing the elimination of a xenobiotic from a poisoned patient is a logical step after techniques to inhibit absorption such as orogastric lavage, activated charcoal, or whole-bowel irrigation have been considered. Table 10–1 lists methods that might be used to enhance elimination. Some of these techniques are described in more detail in chapters that deal with specific xenobiotics. In this chapter, hemodialysis, hemoperfusion, and hemofiltration are considered extracorporeal treatments because xenobiotic removal occurs in a blood circuit outside the body. Currently, these methods are used infrequently because most poisonings are not amenable to removal by these methods. In addition, because these elimination techniques have associated adverse effects and complications, the risk-benefit analysis suggests a benefit in a relatively small proportion of patients. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/03/28 UR - accesspharmacy.mhmedical.com/content.aspx?aid=1108424594 ER -