TY - CHAP M1 - Book, Section TI - Normal Human Microbiota A1 - Carroll, Karen C. A1 - Hobden, Jeffery A. A1 - Miller, Steve A1 - Morse, Stephen A. A1 - Mietzner, Timothy A. A1 - Detrick, Barbara A1 - Mitchell, Thomas G. A1 - McKerrow, James H. A1 - Sakanari, Judy A. PY - 2019 T2 - Jawetz, Melnick, & Adelberg’s Medical Microbiology, 27e AB - The term “normal microbial flora” denotes the population of microorganisms that inhabit the skin and mucous membranes of healthy normal persons. The microorganisms that live inside and on humans (now referred to as the normal microbiota) are estimated to outnumber human somatic and germ cells by a factor of 10. The genomes of these microbial symbionts are collectively defined as the microbiome. Research has shown that the “normal microbiota” provides a first line of defense against microbial pathogens, assist in digestion, play a role in toxin degradation, and contribute to maturation of the immune system. Shifts in the normal microbiota or stimulation of inflammation by these commensals may cause diseases such as bacterial vaginosis, periodontitis, and inflammatory bowel disease. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/03/28 UR - accesspharmacy.mhmedical.com/content.aspx?aid=1114733298 ER -