RT Book, Section A1 Moy, Beverly A1 Goss, Paul A1 Lee, Richard J. A1 Smith, Matthew A2 Brunton, Laurence L. A2 Chabner, Bruce A. A2 Knollmann, Björn C. SR Print(0) ID 1127871809 T1 Natural Products in Cancer Chemotherapy: Hormones and Related Agents T2 Goodman & Gilman's: The Pharmacological Basis of Therapeutics, 12e YR 2015 FD 2015 PB McGraw-Hill Education PP New York, NY SN 9780071624428 LK accesspharmacy.mhmedical.com/content.aspx?aid=1127871809 RD 2023/02/08 AB The growth of a number of cancers is hormone dependent or regulated by hormones. Research in the fields of fertility, birth control, and menopause has yielded valuable hormone analogs and antagonists for the treatment of both breast and prostate cancer. These molecules interrupt the stimulatory axis created by systemic pools of androgens and estrogens, inhibit hormone production or binding to receptors, and ultimately block the complex expression of genes that promotes tumor growth and survival. These drugs have proven effective in extending survival and delaying or preventing tumor recurrence in breast cancer and prostate cancer.