RT Book, Section
A1 King, Michael W.
SR Print(0)
ID 1122103309
T1 Enzymes and Enzyme Kinetics
T2 Integrative Medical Biochemistry Examination and Board Review
YR 2014
FD 2014
PB McGraw-Hill Education
PP New York, NY
SN 9780071786126
LK accesspharmacy.mhmedical.com/content.aspx?aid=1122103309
RD 2020/02/18
AB High-Yield  TermsSimple  enzyme:  binds  only  substrate  and/or  inhibitorsHoloenzyme:  complex  enzymes  which  are  composed  of  protein  plus  a  relatively  small  organic  moleculeApoenzyme:  the  protein  component  of  a  complex  enzymeCoenzymes:  nonprotein  components  of  enzymesIsozyme:  member  of  a  set  of  enzymes  sharing  similar/same  substrate  specificityMetalloenzyme:  enzymes  that  require  a  metal  in  their  compositionRibozymes:  RNA  molecules  that  exhibit  catalytic  activity  in  the  absence  of  any  protein  componentReaction  rate:  described  by  the  number  of  molecules  of  reactant(s)  that  are  converted  into  product(s)  in  a  specified  time  periodChemical  reaction  order:  relates  to  the  number  of  molecules  in  a  reaction  complex  that  can  proceed  to  productEquilibrium  constant:  related  to  the  ratio  of  product  concentration  to  reactant  concentration  or  rate  constants  for  forward  and  reverse  reactionsMichaelis-Menten  constant  (Km):  relates  the  maximum  reaction  velocity  to  substrate  concentration  such  that  Km  is  the  substrate  concentration  [S]  at  which  a  reaction  has  attained  half  the  maximal  velocityLineweaver-Burk  plots:  linear  double  reciprocal  plots  of  substrate  concentration  versus  reaction  velocityAllosteric  enzymes:  defined  as  any  enzyme  whose  activity  is  altered  by  binding  small  molecule  regulators  referred  to  as  effectors;  plots  of  substrate  concentration  versus  reaction  velocity  are  sigmoidal  instead  of  curvilinear