RT Book, Section
A1 King, Michael W.
SR Print(0)
ID 1122104837
T1 Translation: Protein Synthesis and Modification
T2 Integrative Medical Biochemistry Examination and Board Review
YR 2014
FD 2014
PB McGraw-Hill Education
PP New York, NY
SN 9780071786126
LK accesspharmacy.mhmedical.com/content.aspx?aid=1122104837
RD 2024/04/19
AB High-Yield  TermsGenetic  code:  the  genetic  code  defines  the  set  of  rules  (the  nucleotide  triplets)  by  which  information  encoded  within  the  genes  is  translated  into  proteinsWobble  hypothesis:  explains  the  non–Watson-Crick  base-pairing  that  can  occur  between  the  3′-nucleotide  of  a  codon  and  the  5′-nucleotide  of  an  anticodonTernary  complex:  translational  initiation  complex  composed  of  eIF-2  with  GTP  bound  and  the  initiator  methionine  tRNAPeptidyltransferase:  an  RNA-mediated  (ribozyme)  enzymatic  activity  of  the  60S  ribosome  that  catalyzes  transpeptidation  during  protein  elongation.Selenoprotein:  any  of  a  family  of  proteins  that  contain  a  modified  selenocysteine  amino  acidSignal  sequence:  the  N-terminal  15-25  hydrophobic  amino  acids  in  proteins  that  are  destined  for  secretion  of  membrane  insertion;  the  sequences  are  recognized  by  the  signal  recognition  particle  which  assists  in  binding  of  the  ribosome  to  the  ER  membranePrenylation:  posttranslational  modification  by  the  isoprenoid  molecules  farnesyl  or  geranyl  allowing  proteins  to  associate  with  membranesUbiquitin:  a  76-amino-acid  peptide  enzymatically  attached  to  proteins  which,  in  most  cases,  targets  the  modified  protein  for  degradation  in  the  proteosomeProteosome:  a  large  protein  complex  whose  function  is  to  proteolytically  degrade  damaged  or  unneeded  proteins