RT Book, Section
A1 Renslo, Adam
SR Print(0)
ID 1124842078
T1 Preface
T2 The Organic Chemistry of Medicinal Agents
YR 2016
FD 2016
PB McGraw-Hill Education
PP New York, NY
SN 9780071794213
LK accesspharmacy.mhmedical.com/content.aspx?aid=1124842078
RD 2024/04/16
AB The  chemistry  of  carbon-based  molecules—their  structures,  intermolecular  interactions,  and  reactivity—underlies  life  as  we  know  it  and  thus  also  the  beneficial  (and  sometimes  undesired)  effects  of  the  medicines  we  use.  The  fact  that  rather  simple  organic  molecules  can  be  profoundly  effective  in  treating  human  disease  in  all  its  complexity  must  rank  among  the  most  significant  findings  of  medicine  and  basic  science.  For  many  students,  this  realization  foments  a  desire  to  pursue  a  career  in  one  of  the  various  fields  related  to  the  discovery,  study,  or  appropriate  administration  of  medicines.  In  my  own  case,  this  meant  embarking  on  the  study  of  organic  chemistry  and  learning  how  to  synthesize  organic  molecules  in  the  laboratory.  Later,  as  a  medicinal  chemist  working  in  the  pharmaceutical  industry,  I  experienced  the  thrill  of  seeing  a  few  milligrams  (mere  specks!)  of  a  newly  synthesized  compound  cure  an  otherwise  lethal  infection  in  a  mouse.  A  few  such  compounds  would  later  be  destined  for  studies  in  human  patients,  beginning  the  long  and  often  perilous  path  toward  the  approval  of  a  new  drug.