RT Book, Section A1 Stringer, Janet L. SR Print(0) ID 1142820579 T1 Drug Metabolism and Renal Elimination T2 Basic Concepts in Pharmacology: What You Need to Know for Each Drug Class, 5e YR 2017 FD 2017 PB McGraw-Hill Education PP New York, NY SN 9781259861079 LK accesspharmacy.mhmedical.com/content.aspx?aid=1142820579 RD 2024/03/29 AB The liver is a major site for drug metabolism. The goal of metabolism is to produce metabolites that are polar or charged, and can be eliminated by the kidney. Lipid-soluble agents are metabolized by the liver using two general sets of reactions, called phase I and phase II.