RT Book, Section A1 Wells, Barbara G. A1 DiPiro, Joseph T. A1 Schwinghammer, Terry L. A1 DiPiro, Cecily V. SR Print(0) ID 1144733911 T1 Shock T2 Pharmacotherapy Quick Guide YR 2017 FD 2017 PB McGraw-Hill Education PP New York, NY SN 9781259586439 LK accesspharmacy.mhmedical.com/content.aspx?aid=1144733911 RD 2024/04/19 AB Shock is an acute state of inadequate perfusion of critical organs that can lead to death if therapy is not optimal. Shock is defined as systolic blood pressure (SBP) less than 90 mm Hg or reduction of at least 40 mm Hg from baseline with perfusion abnormalities despite adequate fluid resuscitation.