RT Book, Section A1 Wells, Barbara G. A1 DiPiro, Joseph T. A1 Schwinghammer, Terry L. A1 DiPiro, Cecily V. SR Print(0) ID 1144734945 T1 Endocarditis T2 Pharmacotherapy Quick Guide YR 2017 FD 2017 PB McGraw-Hill Education PP New York, NY SN 9781259586439 LK accesspharmacy.mhmedical.com/content.aspx?aid=1144734945 RD 2024/04/19 AB Endocarditis is an inflammation of the endocardium, the membrane lining the chambers of the heart and covering the cusps of the heart valves. Infective endocarditis (IE) refers to infection of the heart valves by microorganisms, primarily bacteria.Endocarditis is often referred to as either acute or subacute depending on the clinical presentation. Acute bacterial endocarditis is a fulminating infection associated with high fevers, systemic toxicity, and death within days to weeks if untreated. Subacute infectious endocarditis is a more indolent infection, usually occurring in a setting of prior valvular heart disease.