RT Book, Section
A1 Beauduy, Camille E.
A1 Winston, Lisa G.
A2 Katzung, Bertram G.
SR Print(0)
ID 1148440397
T1 Antimycobacterial Drugs
T2 Basic & Clinical Pharmacology, 14e
YR 2017
FD 2017
PB McGraw-Hill Education
PP New York, NY
SN 9781259641152
LK accesspharmacy.mhmedical.com/content.aspx?aid=1148440397
RD 2024/04/23
AB CASE  STUDYA  60-year-old  man  presents  to  the  emergency  department  with  a  2-month  history  of  fatigue,  weight  loss  (10  kg),  fevers,  night  sweats,  and  a  productive  cough.  He  is  currently  living  with  friends  and  has  been  intermittently  homeless,  spending  time  in  shelters.  He  reports  drinking  about  6  beers  per  day.  In  the  emergency  department,  a  chest  x-ray  shows  a  right  apical  infiltrate.  Given  the  high  suspicion  for  pulmonary  tuberculosis,  the  patient  is  placed  in  respiratory  isolation.  His  first  sputum  smear  shows  many  acid-fast  bacilli,  and  an  HIV  test  returns  with  a  positive  result.  What  drugs  should  be  started  for  treatment  of  presumptive  pulmonary  tuberculosis?  Does  the  patient  have  a  heightened  risk  of  developing  medication  toxicity?  If  so,  which  medication(s)  would  be  likely  to  cause  toxicity?