RT Book, Section A1 Dietrich, Eric A2 Whalen, Karen A2 Hardin, Heather C. SR Print(0) ID 1150201320 T1 Osteoarthritis MTM Data Set T2 Medication Therapy Management: A Comprehensive Approach, 2e YR 2018 FD 2018 PB McGraw-Hill Education PP New York, NY SN 9781260108453 LK accesspharmacy.mhmedical.com/content.aspx?aid=1150201320 RD 2022/07/01 AB KEY POINTSTreatment goals for osteoarthritis (OA) should be identified prior to beginning treatment and should be individualized on a patient-by-patient basis. An acceptable balance between minimizing pain and side effects, while maximizing functionality and quality of life, should be targeted.Optimal treatment of OA includes both pharmacologic and nonpharmacologic therapies. Adherence to nonpharmacologic treatment should be assessed at each medication therapy management (MTM) encounter.Given the significant adverse effects of chronic treatment with nonsteroidal anti-inflammatory drugs (NSAIDs), reassessment of risk factors such as cardiovascular risk and risk of gastrointestinal bleeding should be conducted during each MTM encounter to ensure safety of continued treatment and potential need for additional medications to reduce risk (eg, proton-pump inhibitors for risk of gastrointestinal bleeding).Assessment of potential adverse effects from analgesic therapy should be determined during each MTM encounter. Importantly, bleeding from NSAIDs or constipation, sedation, and/or respiratory depression associated with opioids should be monitored frequently.