RT Book, Section A1 Gerding, Dale N. A1 Johnson, Stuart A2 Jameson, J. Larry A2 Fauci, Anthony S. A2 Kasper, Dennis L. A2 Hauser, Stephen L. A2 Longo, Dan L. A2 Loscalzo, Joseph SR Print(0) ID 1159153579 T1 Clostridium difficile Infection, Including Pseudomembranous Colitis T2 Harrison's Principles of Internal Medicine, 20e YR 2018 FD 2018 PB McGraw-Hill Education PP New York, NY SN 9781259644016 LK accesspharmacy.mhmedical.com/content.aspx?aid=1159153579 RD 2024/04/24 AB Clostridium difficile infection (CDI) is a unique colonic disease that is acquired most commonly in association with antimicrobial use and the consequent disruption of the normal colonic microbiota. The most commonly diagnosed diarrheal illness acquired in the hospital, CDI results from the ingestion of spores of C. difficile that vegetate, multiply, and secrete toxins, causing diarrhea and, in the most severe cases, pseudomembranous colitis (PMC).