RT Book, Section
A1 Walker, David H.
A1 Dumler, J. Stephen
A1 Blanton, Lucas S.
A1 Marrie, Thomas
A2 Jameson, J. Larry
A2 Fauci, Anthony S.
A2 Kasper, Dennis L.
A2 Hauser, Stephen L.
A2 Longo, Dan L.
A2 Loscalzo, Joseph
SR Print(0)
ID 1160013920
T1 Rickettsial Diseases
T2 Harrison's Principles of Internal Medicine, 20e
YR 2018
FD 2018
PB McGraw-Hill Education
PP New York, NY
SN 9781259644016
LK accesspharmacy.mhmedical.com/content.aspx?aid=1160013920
RD 2024/04/18
AB Rickettsiae  are  a  heterogeneous  group  of  small,  obligately  intracellular,  gram-negative  coccobacilli  and  short  bacilli,  most  of  which  are  transmitted  by  a  tick,  mite,  flea,  or  louse  vector.  Except  in  the  case  of  louse-borne  typhus,  humans  are  incidental  hosts.  Among  rickettsiae,  Coxiella  burnetii,  Rickettsia  prowazekii,  and  Rickettsia  typhi  have  the  well-documented  ability  to  survive  for  an  extended  period  outside  the  reservoir  or  vector  and  to  be  extremely  infectious:  inhalation  of  a  single  Coxiella  microorganism  can  cause  pneumonia.  High-level  infectivity  and  severe  illness  after  inhalation  make  R.  prowazekii,  R.  rickettsii,  R.  typhi,  R.  conorii,  and  C.  burnetii  bioterrorism  threats  (Chap.  S2).