RT Book, Section
A1 Baughman, Robert P.
A1 Lower, Elyse E.
A2 Jameson, J. Larry
A2 Fauci, Anthony S.
A2 Kasper, Dennis L.
A2 Hauser, Stephen L.
A2 Longo, Dan L.
A2 Loscalzo, Joseph
SR Print(0)
ID 1156508267
T1 Sarcoidosis
T2 Harrison's Principles of Internal Medicine, 20e
YR 2018
FD 2018
PB McGraw-Hill Education
PP New York, NY
SN 9781259644016
LK accesspharmacy.mhmedical.com/content.aspx?aid=1156508267
RD 2024/04/16
AB Sarcoidosis  is  an  inflammatory  disease  characterized  by  the  presence  of  noncaseating  granulomas.  The  disease  is  often  multisystem  and  requires  the  presence  of  involvement  in  two  or  more  organs  for  a  specific  diagnosis.  The  finding  of  granulomas  is  not  specific  for  sarcoidosis,  and  other  conditions  known  to  cause  granulomas  must  be  ruled  out.  These  conditions  include  mycobacterial  and  fungal  infections,  malignancy,  and  environmental  agents  such  as  beryllium.  Although  sarcoidosis  can  affect  virtually  every  organ  of  the  body,  the  lung  is  most  commonly  affected.  Other  organs  commonly  affected  are  the  liver,  skin,  and  eye.  The  clinical  outcome  of  sarcoidosis  varies,  with  remission  occurring  in  over  one-half  of  patients  within  a  few  years  of  diagnosis;  however,  the  remaining  patients  may  develop  a  chronic  disease  that  lasts  for  decades.