RT Book, Section
A1 Cryer, Philip E.
A1 Davis, Stephen N.
A2 Jameson, J. Larry
A2 Fauci, Anthony S.
A2 Kasper, Dennis L.
A2 Hauser, Stephen L.
A2 Longo, Dan L.
A2 Loscalzo, Joseph
SR Print(0)
ID 1156520943
T1 Hypoglycemia
T2 Harrison's Principles of Internal Medicine, 20e
YR 2018
FD 2018
PB McGraw-Hill Education
PP New York, NY
SN 9781259644016
LK accesspharmacy.mhmedical.com/content.aspx?aid=1156520943
RD 2024/04/18
AB Hypoglycemia  is  most  commonly  caused  by  drugs  used  to  treat  diabetes  mellitus  or  by  exposure  to  other  drugs,  including  alcohol.  However,  a  number  of  other  disorders,  including  critical  organ  failure,  sepsis  and  inanition,  hormone  deficiencies,  non-β-cell  tumors,  insulinoma,  and  prior  gastric  surgery,  can  cause  hypoglycemia  (Table  399-1).  Hypoglycemia  may  be  documented  by  Whipple’s  triad:  (1)  symptoms  consistent  with  hypoglycemia,  (2)  a  low  plasma  glucose  concentration  measured  with  a  precise  method,  and  (3)  relief  of  symptoms  after  the  plasma  glucose  level  is  raised.  The  lower  limit  of  the  fasting  plasma  glucose  concentration  is  normally  ~70  mg/dL  (~3.9  mmol/L),  but  lower  venous  glucose  levels  occur  normally,  late  after  a  meal,  during  pregnancy,  and  during  prolonged  fasting  (>24  h).  Hypoglycemia  can  cause  serious  morbidity;  if  severe  it  can  be  fatal.  It  should  be  considered  in  any  patient  with  episodes  of  confusion,  an  altered  level  of  consciousness,  or  a  seizure.