RT Book, Section
A1 Kishnani, Priya S.
A1 Chen, Yuan-Tsong
A2 Jameson, J. Larry
A2 Fauci, Anthony S.
A2 Kasper, Dennis L.
A2 Hauser, Stephen L.
A2 Longo, Dan L.
A2 Loscalzo, Joseph
SR Print(0)
ID 1160017961
T1 Glycogen Storage Diseases and Other Inherited Disorders of Carbohydrate Metabolism
T2 Harrison's Principles of Internal Medicine, 20e
YR 2018
FD 2018
PB McGraw-Hill Education
PP New York, NY
SN 9781259644016
LK accesspharmacy.mhmedical.com/content.aspx?aid=1160017961
RD 2024/04/18
AB Carbohydrate  metabolism  plays  a  vital  role  in  cellular  function  by  providing  the  energy  required  for  most  metabolic  processes.  The  relevant  biochemical  pathways  involved  in  the  metabolism  of  these  carbohydrates  are  shown  in  Fig.  412-1.  Glucose  is  the  principal  substrate  of  energy  metabolism  in  humans.  Metabolism  of  glucose  generates  ATP  through  glycolysis  and  mitochondrial  oxidative  phosphorylation.  The  body  obtains  glucose  through  the  ingestion  of  polysaccharides  (primarily  starch)  and  disaccharides  (e.g.,  lactose,  maltose,  and  sucrose).  Lactose  and  fructose  are  two  other  monosaccharides  that  serve  as  sources  of  fuel  for  cellular  metabolism;  however,  their  role  as  fuel  sources  is  much  less  significant  than  that  of  glucose.  Lactose  is  derived  from  galactose  +  glucose,  which  is  found  in  milk  products,  and  is  an  important  component  of  certain  glycolipids,  glycoproteins,  and  glycosaminoglycans.  Fructose  is  found  in  fruits,  vegetables,  and  honey.  Sucrose  (fructose  +  glucose)  is  another  dietary  source  of  fructose  and  is  a  commonly  used  sweetener.