RT Book, Section
A1 Katzung, Bertram G.
A1 Kruidering-Hall, Marieke
A1 Trevor, Anthony J.
SR Print(0)
ID 1156527626
T1 Cholinoceptor-Activating & Cholinesterase-Inhibiting Drugs
T2 Katzung & Trevor's Pharmacology: Examination & Board Review, 12e
YR 2019
FD 2019
PB McGraw-Hill Education
PP New York, NY
SN 9781259641022
LK accesspharmacy.mhmedical.com/content.aspx?aid=1156527626
RD 2024/04/18
AB Drugs  with  acetylcholine-like  effects  (cholinomimetics)  consist  of  2  major  subgroups  on  the  basis  of  their  mode  of  action  (ie,  whether  they  act  directly  at  the  acetylcholine  receptor  or  indirectly  through  inhibition  of  cholinesterase).  Drugs  in  the  direct-acting  subgroup  are  further  subdivided  on  the  basis  of  their  spectrum  of  action  (ie,  whether  they  act  on  muscarinic  or  nicotinic  cholinoceptors).Acetylcholine  may  be  considered  the  prototype  that  acts  directly  at  both  muscarinic  and  nicotinic  receptors.  Neostigmine  is  a  prototype  for  the  indirect-acting  cholinesterase  inhibitors.