RT Book, Section A1 Else, Tobias A1 Hammer, Gary D. A2 Hammer, Gary D. A2 McPhee, Stephen J. SR Print(0) ID 1156659785 T1 Disorders of the Hypothalamus & Pituitary Gland T2 Pathophysiology of Disease: An Introduction to Clinical Medicine, 8e YR 2019 FD 2019 PB McGraw-Hill Education PP New York, NY SN 9781260026504 LK accesspharmacy.mhmedical.com/content.aspx?aid=1156659785 RD 2024/03/28 AB The hypothalamus is the part of the brain where the activity of the autonomic nervous system and endocrine glands, which directly control various systems of the body, is integrated with input from other centers that give rise to emotions and behavior. The hypothalamus thus serves to ensure that (1) the organism responds appropriately to deviations from various internal set points (including those for temperature, volume, osmolality, satiety, and body fat content); (2) the responses to such deviations from a set point include coordinated activity of the nervous and endocrine systems; and (3) the emotions and behavior being manifested are appropriate for reflex responses being triggered to correct the deviations from internal set points. The following description outlines the integrative function of the hypothalamus in regard to the coordination of endocrine and central nervous system (CNS) responses.