RT Book, Section
A1 Hecht, Keith A.
A2 Sutton, S. Scott
SR Print(0)
ID 1158313722
T1 Oncology Overview and Supportive Care
T2 McGraw-Hill's NAPLEX® Review Guide, 3e
YR 2019
FD 2019
PB McGraw-Hill Education
PP New York, NY
SN 9781260135923
LK accesspharmacy.mhmedical.com/content.aspx?aid=1158313722
RD 2022/05/16
AB Modern  medical  science  has  led  to  significant  improvement  in  survival  and  quality  of  life  for  individuals  with  neoplastic  (neoplasm)  conditions.  Neoplasm  (tumor  or  cancer)  is  an  abnormal  mass  of  tissue,  the  growth  of  which  exceeds  and  is  uncoordinated  with  that  of  normal  tissues  and  persists  after  cessation  of  the  stimuli  which  evoked  the  change.  The  key  feature  of  cancer  is  unregulated  cell  division  and  growth,  secondary  to  the  loss  of  normal  control  mechanisms  that  govern  cell  survival,  proliferation,  and  differentiation.  Benign  tumors  are  limited  to  the  tissue  of  origin  and  do  not  invade  surrounding  tissue.  Their  dangerous  counterpart,  malignant  tumors  can  invade  local  tissues  and  undergo  distant  spread  (metastasis).  Malignant  tumors  (often  referred  to  as  cancer)  are  predominantly  of  two  types,  solid  tumors  and  hematologic  malignancies.  Solid  tumors  include  various  types  of  cancer,  typically  arising  from  a  specific  organ  or  site.  They  are  characterized  by  their  initial  location  as  well  as  their  cell  of  origin,  including  carcinomas  (of  epithelial  origin)  and  the  sarcomas  (of  connective  tissue  origin,  mesenchymal  origin).  Hematologic  malignancies  include  cancers  that  arise  from  cells  in  the  hematopoietic  cascade  and  are  most  commonly  categorized  as  leukemias,  lymphomas,  or  myeloma.