RT Book, Section
A1 Sutton, S. Scott
A1 Bland, Christopher M.
A2 Sutton, S. Scott
SR Print(0)
ID 1158314279
T1 Antimicrobial Principles
T2 McGraw-Hill's NAPLEX® Review Guide, 3e
YR 2019
FD 2019
PB McGraw-Hill Education
PP New York, NY
SN 9781260135923
LK accesspharmacy.mhmedical.com/content.aspx?aid=1158314279
RD 2024/04/25
AB Antimicrobials  vary  in  their  ability  to  inhibit  or  kill  different  species  of  bacteria.  Antimicrobials  that  kill  many  different  species  of  bacteria  are  called  broad-spectrum  antimicrobials;  whereas,  antimicrobials  that  kill  fewer  different  species  of  bacteria  are  called  narrow-spectrum  antimicrobials.  Empirically  treating  infectious  diseases  and  monitoring  therapy  requires  knowledge  of  antimicrobial  properties,  host  factors,  patient’s  normal  flora,  differentiating  infection  versus  colonization,  and  understanding  clinical  presentation  and  diagnostic  tests  (microbiologic  and  nonmicrobiologic  laboratory  studies).  Broad-spectrum  antimicrobial  coverage  increases  the  likelihood  of  empirically  targeting  a  causative  pathogen;  unfortunately,  the  development  of  secondary  infections  caused  by  selection  of  antimicrobial-resistant  pathogens  is  a  common  complication.  In  addition,  adverse  events  may  complicate  up  to  10%  of  antimicrobial  therapy  (adverse  event  rate  is  higher  for  select  agents).