RT Book, Section A1 Ware, Kenric B. A2 Sutton, S. Scott SR Print(0) ID 1158314654 T1 Opportunistic Infections T2 McGraw-Hill's NAPLEX® Review Guide, 3e YR 2019 FD 2019 PB McGraw-Hill Education PP New York, NY SN 9781260135923 LK accesspharmacy.mhmedical.com/content.aspx?aid=1158314654 RD 2022/05/17 AB People with healthy immune systems can be exposed to certain viruses, bacteria, or parasites and have minimal reactions to them; however, people living with human immunodeficiency virus (HIV) can face serious health threats from opportunistic infections (OIs). These infections are called opportunistic because they take advantage of a weakened immune system. Opportunistic pathogens are traditionally encountered at CD4 levels below certain thresholds (Figure 28-1). Besides contributing to morbidity and mortality, OIs accelerate the progression of HIV disease. For this reason, guidelines emphasize concurrent antiretroviral therapy (ART) with prophylaxis, treatment, and secondary prophylaxis of OIs.