RT Book, Section
A1 Clements, Jennifer N.
A2 Sutton, S. Scott
SR Print(0)
ID 1158315819
T1 Osteoporosis
T2 McGraw-Hill's NAPLEX® Review Guide, 3e
YR 2019
FD 2019
PB McGraw-Hill Education
PP New York, NY
SN 9781260135923
LK accesspharmacy.mhmedical.com/content.aspx?aid=1158315819
RD 2024/04/25
AB Osteoporosis  is  a  reduction  in  bone  mineral  density  (BMD),  loss  of  bone  strength,  and  deterioration  of  the  skeletal  microarchitecture  resulting  in  fragile  bones.  Due  to  a  decrease  in  bone  strength  and  loss  of  bone  quality,  there  is  an  increased  risk  of  fractures,  particularly  of  the  hip,  spine,  and  wrist.  Women  have  a  higher  risk  of  an  osteoporotic  fracture  per  year,  compared  to  men;  however,  men  have  a  higher  mortality  associated  with  an  osteoporotic  fracture.  There  are  two  types  of  bone  in  the  human  skeleton—cortical  and  trabecular.  Cortical  bone,  or  compact  bone,  is  a  dense,  strong  bone  and  forms  the  outer  shell  found  in  long  and  flat  bones.  Cortical  bone  accounts  for  bone  strength  and  is  80%  of  the  weight  for  the  human  skeleton.  Trabecular  bone,  also  known  as  cancellous  bone,  is  porous  (ie,  sponge-like).  This  type  of  bone  is  soft,  weak,  and  flexible  and,  therefore,  susceptible  to  fracture.  Trabecular  bone  is  on  interior  surfaces  of  long  bones,  vertebrae,  and  distal  forearms.