RT Book, Section A1 Kerr, Jessica L. A2 Sutton, S. Scott SR Print(0) ID 1158316403 T1 Diabetes Mellitus T2 McGraw-Hill's NAPLEX® Review Guide, 3e YR 2019 FD 2019 PB McGraw-Hill Education PP New York, NY SN 9781260135923 LK accesspharmacy.mhmedical.com/content.aspx?aid=1158316403 RD 2024/04/18 AB Diabetes mellitus (DM) is a group of metabolic disorders characterized by high blood glucose as well as altered fat and protein metabolism that results from defects in insulin secretion, insulin action (sensitivity), or both. Type 1 diabetes mellitus (T1DM) characterized by insulin deficient and type 2 diabetes mellitus (T2DM) characterized by insulin resistance combined with beta cell dysfunction. Additional subclasses include gestational diabetes mellitus (GDM) and secondary diabetes associated with hormonal syndromes, medications, and diseases of the pancreas. The key differences between T1DM and T2DM are the pathophysiology, etiology of hyperglycemia, and clinical presentation; however, both are associated with microvascular and macrovascular complications.