RT Book, Section
A1 Barrett, Kim E.
A1 Barman, Susan M.
A1 Brooks, Heddwen L.
A1 Yuan, Jason X.-J.
SR Print(0)
ID 1159053161
T1 The Thyroid Gland
T2 Ganong's Review of Medical Physiology, 26e
YR 2019
FD 2019
PB McGraw-Hill Education
PP New York, NY
SN 9781260122404
LK accesspharmacy.mhmedical.com/content.aspx?aid=1159053161
RD 2024/04/19
AB OBJECTIVESAfter  studying  this  chapter,  you  should  be  able  to:Describe  the  development,  anatomy,  and  histology  of  the  thyroid  gland,  and  how  these  relate  to  its  function,  as  well  as  the  changes  in  histology  that  accompany  the  activation  of  secretion  with  reabsorption  of  thyroglobulin  from  the  colloid.Define  the  chemical  nature  of  the  thyroid  hormones  and  how  they  are  synthesized.  Understand  the  critical  role  of  iodine  in  the  thyroid  gland  and  how  its  transport  is  controlled,  as  well  as  how  it  is  incorporated  into  the  tyrosine  residues  of  thyroglobulin  at  the  interface  between  thyrocytes  and  colloid  via  the  process  of  organification.Describe  the  relative  roles  of  binding  to  albumin,  transthyretin,  and  thyroxine-binding  globulin  in  the  transport  of  thyroid  hormones,  the  availability  of  free  hormones,  and  peripheral  metabolism.Identify  the  role  of  the  hypothalamus  and  pituitary  in  regulating  thyroid  function  and  the  feedback  loops  that  establish  the  level  of  secretion  of  thyroid  hormones.Define  the  effects  of  the  thyroid  hormones  in  homeostasis,  metabolism,  and  growth.Understand  the  basis  of  conditions  where  thyroid  function  is  abnormal  and  how  they  can  be  treated.