RT Book, Section A1 Barrett, Kim E. A1 Barman, Susan M. A1 Brooks, Heddwen L. A1 Yuan, Jason X.-J. SR Print(0) ID 1159054220 T1 Transport & Metabolic Functions of the Liver T2 Ganong's Review of Medical Physiology, 26e YR 2019 FD 2019 PB McGraw-Hill Education PP New York, NY SN 9781260122404 LK accesspharmacy.mhmedical.com/content.aspx?aid=1159054220 RD 2024/04/24 AB OBJECTIVESAfter studying this chapter, you should be able to:Understand the functional anatomy of the liver and the relative arrangements of hepatocytes, cholangiocytes, endothelial cells, and Kupffer cells.Define the characteristics of the hepatic circulation and its role in subserving the liver’s functions.Describe the major functions of the liver with respect to metabolism, detoxification, and excretion of hydrophobic substances.Identify the plasma proteins that are synthesized by the liver.Outline the mechanisms by which the liver contributes to whole body ammonia homeostasis and the consequences of the failure of these mechanisms, particularly for brain function.Describe the constituents of bile, its formation, and its role in the excretion of cholesterol and bilirubin.Identify the mechanisms that permit normal functioning of the gallbladder and the basis of gallstone disease.