RT Book, Section A1 Stolbach, Andrew A1 Hoffman, Robert S. A2 Nelson, Lewis S. A2 Howland, Mary Ann A2 Lewin, Neal A. A2 Smith, Silas W. A2 Goldfrank, Lewis R. A2 Hoffman, Robert S. SR Print(0) ID 1163009332 T1 Respiratory Principles T2 Goldfrank's Toxicologic Emergencies, 11e YR 2019 FD 2019 PB McGraw-Hill Education PP New York, NY SN 9781259859618 LK accesspharmacy.mhmedical.com/content.aspx?aid=1163009332 RD 2024/03/28 AB The primary function of the lungs is gas exchange. Specifically, this involves the transport of oxygen (O2) into the blood, and the elimination of carbon dioxide (CO2) from the blood. In addition, the lungs serve as minor organs of metabolism and elimination for a number of xenobiotics, a source of insensible water loss, and a means of temperature regulation. Air is conducted through proximal airways, made up of columnar epithelium and mucin-secreting goblet cells. Oxygen exchange occurs in distal airways, through type I pneumocytes, which make up most of alveolar surface area. Type II pneumocytes, which secrete surfactant, take up less pulmonary surface area.