RT Book, Section
A1 Geyer, Howard L.
A2 Nelson, Lewis S.
A2 Howland, Mary Ann
A2 Lewin, Neal A.
A2 Smith, Silas W.
A2 Goldfrank, Lewis R.
A2 Hoffman, Robert S.
SR Print(0)
ID 1163010702
T1 Botulism
T2 Goldfrank's Toxicologic Emergencies, 11e
YR 2019
FD 2019
PB McGraw-Hill Education
PP New York, NY
SN 9781259859618
LK accesspharmacy.mhmedical.com/content.aspx?aid=1163010702
RD 2024/04/24
AB Botulism,  a  potentially  fatal  neuroparalytic  illness,  results  from  exposure  to  botulinum  neurotoxin  (BoNT),  which  is  produced  by  the  bacterium  Clostridium  botulinum  and  other  Clostridium  species.  The  earliest  cases  of  botulism  were  described  in  Europe  in  1735  and  were  attributed  to  improperly  preserved  German  sausage;  the  name  of  the  disease  alludes  to  this  association  because  botulus  is  the  Latin  word  for  sausage.  Emile  van  Ermengem  identified  the  causative  organism  in  1897  and  named  it  Bacillus  botulinum;  it  was  later  renamed  Clostridium  botulinum.25  These  gram-positive,  spore-forming  bacteria  produce  eight  serotypes  of  BoNT,  denoted  A  through  H.88,134