RT Book, Section
A1 Wang, Richard Y.
A2 Nelson, Lewis S.
A2 Howland, Mary Ann
A2 Lewin, Neal A.
A2 Smith, Silas W.
A2 Goldfrank, Lewis R.
A2 Hoffman, Robert S.
SR Print(0)
ID 1163012260
T1 Methotrexate, 5-Fluorouracil, and Capecitabine
T2 Goldfrank's Toxicologic Emergencies, 11e
YR 2019
FD 2019
PB McGraw-Hill Education
PP New York, NY
SN 9781259859618
LK accesspharmacy.mhmedical.com/content.aspx?aid=1163012260
RD 2024/04/20
AB Methotrexate  and  the  fluoropyrimidines  (5-fluorouracil  and  capecitabine)  belong  to  the  chemotherapeutic  class  of  antimetabolites.  Patients  affected  by  these  chemotherapeutics  present  with  significant  clinical  toxicities  that  are  potentially  fatal.  Clinicians  must  recognize  these  patients  early  and  be  prepared  to  provide  immediate  interventions  that  include  specific  antidotal  therapies.  The  oral  formulations  of  methotrexate  and  capecitabine  present  a  risk  for  intentional  or  unintentional  chemotherapeutics  ingestion  in  the  home.