RT Book, Section
A1 Riedel, Stefan
A1 Hobden, Jeffery A.
A1 Miller, Steve
A1 Morse, Stephen A.
A1 Mietzner, Timothy A.
A1 Detrick, Barbara
A1 Mitchell, Thomas G.
A1 Sakanari, Judy A.
A1 Hotez, Peter
A1 Mejia, Rojelio
SR Print(0)
ID 1163282101
T1 Parvoviruses
T2 Jawetz, Melnick, & Adelberg's Medical Microbiology, 28e
YR 2019
FD 2019
PB McGraw-Hill Education
PP New York, NY
SN 9781260012026
LK accesspharmacy.mhmedical.com/content.aspx?aid=1163282101
RD 2024/04/18
AB Parvoviruses  are  the  smallest  DNA  animal  viruses.  Because  of  the  limited  coding  capacity  of  their  genome,  viral  replication  is  dependent  on  functions  supplied  by  replicating  host  cells  or  by  coinfecting  helper  viruses.  Parvovirus  B19  is  pathogenic  for  humans  and  has  a  tropism  for  erythroid  progenitor  cells.  It  is  the  cause  of  erythema  infectiosum  (“Fifth  disease”),  a  common  childhood  exanthem;  a  polyarthralgia–arthritis  syndrome  in  normal  adults;  aplastic  crisis  in  patients  with  hemolytic  disorders;  chronic  anemia  in  immunocompromised  individuals;  and  fetal  death.  The  human  bocaviruses  have  been  detected  in  respiratory  specimens  from  children  with  acute  respiratory  disease  and  in  stool  samples,  but  a  role  in  disease  is  unproven.