RT Book, Section A1 Riedel, Stefan A1 Hobden, Jeffery A. A1 Miller, Steve A1 Morse, Stephen A. A1 Mietzner, Timothy A. A1 Detrick, Barbara A1 Mitchell, Thomas G. A1 Sakanari, Judy A. A1 Hotez, Peter A1 Mejia, Rojelio SR Print(0) ID 1163284258 T1 AIDS and Lentiviruses T2 Jawetz, Melnick, & Adelberg's Medical Microbiology, 28e YR 2019 FD 2019 PB McGraw-Hill Education PP New York, NY SN 9781260012026 LK accesspharmacy.mhmedical.com/content.aspx?aid=1163284258 RD 2024/04/23 AB Human immunodeficiency virus (HIV) types, derived from primate lentiviruses, are the etiologic agents of Acquired Immune Deficiency Syndrome (AIDS). The illness was first described in 1981, and HIV-1 was isolated by the end of 1983. Since then, AIDS has become a worldwide epidemic, expanding in scope and magnitude as HIV infections have affected different populations and geographic regions. Millions are now infected worldwide; once infected, individuals remain infected for life. Within a decade, if left untreated, the vast majority of HIV-infected individuals develop fatal opportunistic infections as a result of HIV-induced deficiencies in the immune system. AIDS is one of the most important public health problems worldwide at the start of the 21st century. The development of highly active antiretroviral therapy (HAART) for chronic suppression of HIV replication and prevention of AIDS has been a major achievement in HIV medicine.