RT Book, Section A1 Sandmann, Beverly J. A1 Dash, Alekha K. A1 Al-Achi, Antoine A1 Greenwood, Robert A2 Mobley, W. Cary A2 Amiji, Mansoor M. A2 Cook, Thomas J. SR Print(0) ID 1163540237 T1 Ionic Equilibria and Buffers T2 Applied Physical Pharmacy, 3e YR 2019 FD 2019 PB McGraw-Hill Education PP New York, NY SN 9781260452211 LK accesspharmacy.mhmedical.com/content.aspx?aid=1163540237 RD 2024/03/29 AB Learning ObjectivesAfter completing this chapter, the reader should be able to:Define a strong electrolyte, a weak electrolyte, and a nonelectrolyte.Differentiate between a cation and an anion.Define an acid, a base, and the different types of salts.Recognize and give examples of pharmaceutically important acids, bases, and salts.Describe the ionization equilibria of strong and weak electrolytes.Calculate and interpret the ionization constants of weak acids and bases (Ka, Kb, pKa, and pKb).Calculate the pH and pOH and the concentrations of the components of aqueous solutions of weak electrolytes.Calculate the pH and pOH of mixtures of weak acids and bases, diprotic acids, and ampholyte solutions.Calculate the percent ionization of weak electrolytes as a function of pH.Describe the physiologic implications of percentage of ionization of weak electrolytes in the absorption, transport, and excretion of drugs (pH partition hypothesis).Define a buffer solution and list its components.Calculate the pH of a buffer solution.Define and calculate the buffer capacity of a buffer solution.Calculate the quantity of ingredients needed to prepare a buffer solution.Recognize the various types of buffer solutions and their methods of preparation.Define ionic strength and understand its effect on ionization.